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Overview

Course Prescription

Biological information is coded in and expressed from genomes. This course explores methods for detecting structural and functional elements of genomes, plus the wider genome biology of eukaryotic and prokaryotic systems. Students will learn how genomic data is generated and analysed, how genomes evolve, and how genomic information is expressed and regulated.

Course Overview

Nau mai, haere mai! Welcome to BIOSCI 355!

Building on the foundations established in BIOSCI 202, this course aims to develop a comprehensive understanding of what makes up genomes and how and why genomes change over time. It will also explore where the current limits of our knowledge about genomes are. The course compares and contrasts prokaryote and eukaryote genomes, including why they might differ. In doing so, it uses examples from the latest research, including molecular genomics, DNA sequence analysis, transcriptomics, computational biology, and comparative genomics. In the lab component, you will undertake an actual research project, using cutting-edge molecular genomics and computational techniques to synthesize your own random DNA sequences and evaluate the effects of expressing them on organisms. This hands-on experience is designed to equip you with essential practical skills in both experimental and computational genome biology.


Career pathways:

  • Genetics/genomics researcher
  • Computational biologist/bioinformatician
  • Technologist/biotechnologist
  • Genomic medicine research
  • Ethical, Legal, and Social Implications Research

Key Topics

We will cover four broad topics:

  • Introduction to genomes
  • Introduction to transcriptomics
  • Eukaryote genome biology
  • Prokaryote genome biology


The course is a mix of lectures (2 lectures per week), tutorials (1 tutorial per week), and weekly experimental or computational labs (1 lab per week). The labs develop your practical lab skills for genomics and computational skills to analyse genomic data. The tutorials will give you practical 'under the hood' knowledge of how we analyse genomic data, assuming no prior knowledge.

Course Contacts

Course Director: Nobuto Takeuchi (nobuto.takeuchi@auckland.ac.nz)

Workload Expectations

This course is a standard 15 point course and students are expected to spend 10 hours per week involved in each 15 point course that they are enrolled in.

Each week you can expect 2 hours of lectures, a 1 hour tutorial, a 3 hour lab, 2 hours of reading and thinking about the content and 2 hours of work on assignments and/or test preparation.

Course Prerequisites, Corequisites and Restrictions

Prerequisite
Restriction

Advice on Course Limits

This is a limited entry course: there is a limit on the number of enrolments due to staff or space capacity. In cases where the courses is taught under two separate codes (e.g. concurrently taught courses, general education courses) the course limit specified is the total across both versions of the course. For more information, please see the Programme and Course Limitations section of the University Academic and General Statutes and Regulations.

Locations and Semesters Offered

LocationSemester
City

Teaching and Learning

Campus Experience

Attendance at scheduled laboratory sessions is required to complete & receive credit for components of the course.
Lectures and tutorials will be available as recordings.
The activities for the course are scheduled as a standard weekly timetable.

Learning Resources

Taught courses use a learning and collaboration tool called Canvas to provide students with learning materials including reading lists and lecture recordings (where available). Please remember that the recording of any class on a personal device requires the permission of the instructor.

Additional Information on Learning Resources

There is no essential text for the course. We will cross-reference the below recommended texts where relevant. Lecturers will provide links within the modules to key readings.Recommended course texts:Genomes 5 - T.A. BrownIntroduction to Genetic Analysis (9th or 10th ed.) - Griffiths, Wessler, Carroll, DoebleyGenetics: A Conceptual Approach (6th edition). B.A. Pierce

Copyright

The content and delivery of content in this course are protected by copyright. Material belonging to others may have been used in this course and copied by and solely for the educational purposes of the University under license. You may copy the course content for the purposes of private study or research, but you may not upload onto any third-party site, make a further copy or sell, alter or further reproduce or distribute any part of the course content to another person.

Learning Continuity

In the event of an unexpected disruption, we undertake to maintain the continuity and standard of teaching and learning in all your courses throughout the year. If there are unexpected disruptions the University has contingency plans to ensure that access to your course continues and course assessment continues to meet the principles of the University’s assessment policy. Some adjustments may need to be made in emergencies. You will be kept fully informed by your course co-ordinator/director, and if disruption occurs you should refer to the university website for information about how to proceed.

Academic Integrity

The University of Auckland will not tolerate cheating, or assisting others to cheat, and views cheating in coursework as a serious academic offence. The work that a student submits for grading must be the student's own work, reflecting their learning. Where work from other sources is used, it must be properly acknowledged and referenced. This requirement also applies to sources on the internet. A student's assessed work may be reviewed for potential plagiarism or other forms of academic misconduct, using computerised detection mechanisms.

Similarly, research students must meet the University’s expectations of good research practice. This requires:

  • Honesty - in all aspects of research work
  • Accountability - in the conduct of research
  • Professional courtesy and fairness – in working with others
  • Good stewardship – on behalf of others
  • Transparency – of research process and presentation of results
  • Clarity - communication to be understandable, explainable and accessible

For more information on the University’s expectations of academic integrity, please see the Academic Conduct section of the University policy hub.

Disclaimer

Elements of this outline may be subject to change. The latest information about taught courses is made available to enrolled students in Canvas.

Students may be asked to submit assessments digitally. The University reserves the right to conduct scheduled tests and examinations online or through the use of computers or other electronic devices. Where tests or examinations are conducted online remote invigilation arrangements may be used. In exceptional circumstances changes to elements of this course may be necessary at short notice. Students enrolled in this course will be informed of any such changes and the reasons for them, as soon as possible, through Canvas.


Assessment and Learning Outcomes

Course Learning Outcomes

CLO #OutcomeProgramme Capability Link
1
2
3
4
5
6
7
8

Assessments

Assessment TypeAssessment PercentageAssessment Classification

Additional Information on Assessment

Students must pass the practical components (laboratory assessments, tutorial assignments) and the theory components (in-course test, exam) independently to pass the course overall.

Special Requirements

Attendance is required at the evening test (after 6pm); the date and time for the test are published on the BIOSCI 355 Canvas course. Some of the practical work will be undertaken in a PC1 containment facility. Information on how to work safely and in compliance with regulatory requirements will be provided in the laboratory sessions.

Assessment to CLO Mapping

Assessment Type12345678

Student Feedback, Support and Charter

Student Feedback

Feedback on taught courses is gathered from students at the end of each semester through a tool called SET or Qualtrics. The lecturers and course co-ordinators will consider all feedback and respond with summaries and actions. Your feedback helps teachers to improve the course and its delivery for future students. In addition, class Representatives in each class can take feedback to the department and faculty staff-student consultative committees.

Additional Information on Student Feedback

Staff welcome feedback on the course throughout the semester, including the SET evaluations. Please contact your course coordinator or student representative at any time with your feedback.

Class representatives

Class representatives are students tasked with representing student issues to departments, faculties, and the wider university. If you have a complaint about this course, please contact your class rep who will know how to raise it in the right channels. See your departmental noticeboard for contact details for your class reps.

Tuākana

Tuākana is a multi-faceted programme for Māori and Pacific students providing topic specific tutorials, one-on-one sessions, test and exam preparation and more. Explore your options at Tuakana Learning Communities.

Inclusive Learning

All students are asked to discuss any impairment related requirements privately, face to face and/or in written form with the course coordinator, lecturer or tutor. Student Disability Services also provides support for students with a wide range of impairments, both visible and invisible, to succeed and excel at the University. For more information and contact details, please visit the Student Disability Services’ website.

Wellbeing

We all go through tough times during the semester, or see our friends struggling. There is lots of help out there - please see the Support Services page for information on support services in the University and the wider community.

Special Circumstances

If your ability to complete assessed work is affected by illness or other personal circumstances outside of your control, contact a member of teaching staff as soon as possible before the assessment is due. If your personal circumstances significantly affect your performance, or preparation, for an exam or eligible written test, refer to the University’s aegrotat or compassionate consideration page. This should be done as soon as possible and no later than seven days after the affected test or exam date.

Student Charter and Responsibilities

The Student Charter assumes and acknowledges that students are active participants in the learning process and that they have responsibilities to the institution and the international community of scholars. The University expects that students will act at all times in a way that demonstrates respect for the rights of other students and staff so that the learning environment is both safe and productive. For further information visit Student Charter.

Student Academic Complaints and Disputes

Students with concerns about teaching including how a course is delivered, the resources provided, or supervision arrangements, have the right to express their concerns and seek resolution. The university encourages informal resolution where possible, as this is quicker and less stressful. For information on the informal and formal complaints processes, please refer to the Student Academic Complaints Statute in the Student Policies and Guidelines section of the Policy Hub.