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Overview

Course Prescription

Explores the cellular and molecular mechanisms of drug action with a focus on G-protein coupled receptors and biochemical targets for cancer therapy. Drug design is considered from the perspective of in silico modelling, biochemical assessment and intracellular signalling.

Course Overview

MEDSCI 319 explores aspects of molecular pharmacology ranging from understanding the molecular interactions involved in drug binding, to designing and performing experiments that explore authentic hypotheses of drug action. It covers different types of assays and data analysis required to obtain pharmacological parameters used in research applications. MEDSCI 319 follows an integrated course design where content is delivered through a combination of in-class lectures, lectorials, workshops, and laboratory practical exercises to support learning and integration of pharmacological principles. MEDSCI 319 uses examples of kinase drug targets in cancer and  G-protein coupled receptor targets of  psychoactive drugs to place pharmacological theory and practice into real world application.

Course Contacts

Directors

Assoc. Prof. Jack Flanagan (Dept of Pharmacology and Clinical Pharmacology)

Email: j.flanagan@auckland.ac.nz


Dr Raewyn Poulsen (Dept of Pharmacology and Clinical Pharmacology)

Email: r.poulsen@auckland.ac.nz 


Course Coordinators and Professional Teaching Fellows

Dr Deanna Bell (Dept of Pharmacology and Clinical Pharmacology)

Email d.bell@auckland.ac.nz


Dr Leslie Schwarcz (Dept of Pharmacology and Clinical Pharmacology)

Email l.schwarcz@auckland.ac.nz

Workload Expectations

This course is a standard 15 point course and students are expected to spend 10 hours per week involved in each 15 point course that they are enrolled in.

For this course, you can expect 24 hours of formal lectures/lectorials, 33 hours of workshops/practical laboratory work, 30 hours of reading and thinking about the content, and 63 hours of work on assignments and assessment test preparation. The course content is delivered through two hours of lectures and three hours of laboratory or workshop exercises per week. An additional one hour per week is timetabled in SSO and are non-recorded office hours for informal student guided-discussion of the course content.  

Course Prerequisites, Corequisites and Restrictions

Prerequisite
Restriction

Advice on Course Limits

This is a limited entry course: there is a limit on the number of enrolments due to staff or space capacity. In cases where the courses is taught under two separate codes (e.g. concurrently taught courses, general education courses) the course limit specified is the total across both versions of the course. For more information, please see the Programme and Course Limitations section of the University Academic and General Statutes and Regulations.

Locations and Semesters Offered

LocationSemester
Grafton

Teaching and Learning

Campus Experience

Attendance is required at scheduled activities including labs/tutorials/workshops to complete components of the course.

Lectures will be available as recordings. Other learning activities including labs/tutorials/workshops will not be available as recordings.

The course will include live online events including group discussions/tutorials/office hours.

Attendance on campus is required for tests.

The activities for the course are scheduled as a standard weekly timetable.

Tests are undertaken in the class room or laboratory environment.

The final exam is in person.

Assessments held in MEDSCI319 lecture slots are compulsory, as are ALL laboratory sessions. Concessions will NOT be granted for MEDSCI 319 laboratory clashes. In the event that a clashing course holds an assessment at the same time as a compulsory element in MEDSCI 319, restreaming requests will not be accommodated. Therefore, you should choose your courses/lab streams carefully to avoid clashes. Contact course co-ordinators directly for test dates before enrolling in any clashing courses.

Learning Resources

Taught courses use a learning and collaboration tool called Canvas to provide students with learning materials including reading lists and lecture recordings (where available). Please remember that the recording of any class on a personal device requires the permission of the instructor.

Copyright

The content and delivery of content in this course are protected by copyright. Material belonging to others may have been used in this course and copied by and solely for the educational purposes of the University under license.


You may copy the course content for the purposes of private study or research, but you may not upload onto any third-party site, make a further copy or sell, alter or further reproduce or distribute any part of the course content to another person.

Learning Continuity

In the event of an unexpected disruption, we undertake to maintain the continuity and standard of teaching and learning in all your courses throughout the year. If there are unexpected disruptions the University has contingency plans to ensure that access to your course continues and course assessment continues to meet the principles of the University’s assessment policy. Some adjustments may need to be made in emergencies. You will be kept fully informed by your course co-ordinator/director, and if disruption occurs you should refer to the university website for information about how to proceed.

Other Information

MEDSCI 319 is required for the following degrees/pathways:

  • BSc Pharmacology Major (plus MEDSCI 318; Pharmacokinetics and Drug Toxicity and MEDSCI 320; Pharmacology of the Brain and Body) 
  • PHARMCOL 399:Capstone Integrated Pharmacology
  • BioMed Cancer Biology and Therapeutics Specialisation Pathway (plus MEDSCI 356; Developmental Biology and Cancer, MEDSCI 302; Cancer Biology and BIOMED399:Capstone Biomedical Science)

Academic Integrity

The University of Auckland will not tolerate cheating, or assisting others to cheat, and views cheating in coursework as a serious academic offence. The work that a student submits for grading must be the student's own work, reflecting their learning. Where work from other sources is used, it must be properly acknowledged and referenced. This requirement also applies to sources on the internet. A student's assessed work may be reviewed for potential plagiarism or other forms of academic misconduct, using computerised detection mechanisms.

Similarly, research students must meet the University’s expectations of good research practice. This requires:

  • Honesty - in all aspects of research work
  • Accountability - in the conduct of research
  • Professional courtesy and fairness – in working with others
  • Good stewardship – on behalf of others
  • Transparency – of research process and presentation of results
  • Clarity - communication to be understandable, explainable and accessible

For more information on the University’s expectations of academic integrity, please see the Academic Conduct section of the University policy hub.

Disclaimer

Elements of this outline may be subject to change. The latest information about taught courses is made available to enrolled students in Canvas.

Students may be asked to submit assessments digitally. The University reserves the right to conduct scheduled tests and examinations online or through the use of computers or other electronic devices. Where tests or examinations are conducted online remote invigilation arrangements may be used. In exceptional circumstances changes to elements of this course may be necessary at short notice. Students enrolled in this course will be informed of any such changes and the reasons for them, as soon as possible, through Canvas.


Additional Information on Academic integrity

In the event of concerns about the integrity of a student's work, we reserve the right to: view drafts and/or re-assess the student's understanding. Academic misconduct proceedings may be undertaken. Use of AI is permitted on some assessments with limits; these are delineated on a Canvas page.

Assessment and Learning Outcomes

Course Learning Outcomes

CLO #OutcomeProgramme Capability Link
1
2
3
4
5
6
7

Assessments

Assessment TypeAssessment PercentageAssessment Classification

Additional Information on Assessment

Assessment "Must-Pass" Regulations; to pass the course you MUST:

Achieve at least 45% collectively across the tests and exam (mid-semester test, lab test, exam)

Attend a minimum of 75% of the workshop/lab sessions.

Achieve a minimum of 50% in the course overall.

Assessment to CLO Mapping

Assessment Type1234567

Student Feedback, Support and Charter

Student Feedback

Feedback on taught courses is gathered from students at the end of each semester through a tool called SET or Qualtrics. The lecturers and course co-ordinators will consider all feedback and respond with summaries and actions. Your feedback helps teachers to improve the course and its delivery for future students. In addition, class Representatives in each class can take feedback to the department and faculty staff-student consultative committees.

Additional Information on Student Feedback

MEDSCI 319 students in 2024 found satisfaction with the course, with respondents appreciating the highly integrated nature of the course content across the lectures, lectorials, workshops and laboratory-based practical components.

The 2025 edition of MEDSCI 319 is in-person format for lectures, lectorials, workshops and laboratory practical while maintaining some teaching and learning concepts developed through on-line delivery during 2022.

Class representatives

Class representatives are students tasked with representing student issues to departments, faculties, and the wider university. If you have a complaint about this course, please contact your class rep who will know how to raise it in the right channels. See your departmental noticeboard for contact details for your class reps.

Additional Information on Class Representatives

Class rep details can be found on the MEDSCI 319 Canvas Page under 'Contact Us'. 

Tuākana

Tuākana is a multi-faceted programme for Māori and Pacific students providing topic specific tutorials, one-on-one sessions, test and exam preparation and more. Explore your options at Tuakana Learning Communities.

Inclusive Learning

All students are asked to discuss any impairment related requirements privately, face to face and/or in written form with the course coordinator, lecturer or tutor.

Student Disability Services also provides support for students with a wide range of impairments, both visible and invisible, to succeed and excel at the University. For more information and contact details, please visit the Student Disability Services’ website.

Wellbeing

We all go through tough times during the semester, or see our friends struggling. There is lots of help out there - please see the Support Services page for information on support services in the University and the wider community.

Special Circumstances

If your ability to complete assessed work is affected by illness or other personal circumstances outside of your control, contact a member of teaching staff as soon as possible before the assessment is due. If your personal circumstances significantly affect your performance, or preparation, for an exam or eligible written test, refer to the University’s aegrotat or compassionate consideration page. This should be done as soon as possible and no later than seven days after the affected test or exam date.

Additonal Information on Special Circumstances

Only one test (Mid-semester Test OR Lab Test) can be assessed via aegrotat. In the event of an aegrotat application, only comparable pieces of assessment will be used.

Student Charter and Responsibilities

The Student Charter assumes and acknowledges that students are active participants in the learning process and that they have responsibilities to the institution and the international community of scholars. The University expects that students will act at all times in a way that demonstrates respect for the rights of other students and staff so that the learning environment is both safe and productive. For further information visit Student Charter.

Student Academic Complaints and Disputes

Students with concerns about teaching including how a course is delivered, the resources provided, or supervision arrangements, have the right to express their concerns and seek resolution. The university encourages informal resolution where possible, as this is quicker and less stressful. For information on the informal and formal complaints processes, please refer to the Student Academic Complaints Statute in the Student Policies and Guidelines section of the Policy Hub.